Who We Are
We are focused on disrupting heart valve disease and restoring healthy heart function. Our team focuses on tackling clinical gaps and redefining positive outcomes by developing cutting-edge solutions designed to mimic the heart’s native physiology.
News, Presentations and Interviews
News, Presentations and Interviews
October 27, 2025
The PARADIGM Trial is the first head-to-head TAVR trial of its kind. The trial will move beyond conventional endpoints of safety, efficacy, and hemodynamic performance, aiming to also uncover the clinical impact of restoring physiologic flow patterns.
Presented at TCT and sponsored by Anteris, Dr. Miho Fukui’s research focuses on a new concept that uses a percentage in aortic valve area (AVA) reduction for determining disease severity, rather than applying the same AVA cutoffs to all patients despite different valve sizes.
At TCT, Dr. Rishi Puri presented data from DurAVR® THV clinical experience, demonstrating a favorable hemodynamic profile for 37 patients sustained to 1-year follow-up.
One-year Results Highlights:
Anteris Technologies Global Corp. announces that on September 29, 2025, the Company held a Special Meeting of Stockholders (the Special Meeting) at which a quorum was present. The matters listed below were submitted to a vote of the Company’s stockholders at the Special Meeting through the solicitation of proxies. Detailed descriptions of the proposals are included in the Company’s definitive proxy statement on Schedule 14A filed with the Securities and Exchange Commission on August 18, 2025 (the “Proxy Statement”).
A total of 18,687,740 shares of the Company’s common stock were present at the Special Meeting in person, by virtual attendance, or by proxy, which represents approximately 51.8% of the shares of common stock outstanding as of August 11, 2025, which was the record date for the Special Meeting.
A recording of the meeting will be available at this link for 90 days after the meeting.
In this whitepaper, we review the pathophysiology of aortic stenosis—including upstream and downstream consequences of turbulent flow—and offer hypotheses around the impacts of TAVR design on flow patterns and disease regression.
We will explore answers to questions like:
At Sydney Valves, Dr. Rishi Puri presented data from DurAVR® THV clinical experience, demonstrating a favorable hemodynamic profile for 37 patients sustained to 1-year follow-up.
One-year Results Highlights:
“The one-year data for DurAVR® THV continues to validate its groundbreaking hemodynamic performance, demonstrating sustained excellent effective orifice area (EOA) and low mean gradients. Most notably, this is the only transcatheter valve to show zero prosthesis-patient mismatch (PPM) in small annuli patients—an achievement that sets a new standard in TAVR. PPM is a well-established predictor of valve failure and disease progression, and eliminating it has profound implications for long-term patient outcomes. These results reinforce the transformative potential of DurAVR® as we move toward pivotal trials.” - Christopher Meduri, Anteris Chief Medical Officer
At London Valves 2024, Dr. Pankaj Garg presented cutting-edge cardiac MRI analyses, which compared flow dynamics and LV function between DurAVR® THV recipients and a healthy control group. These promising data highlight the potential of DurAVR® THV to mimic the performance of a healthy aortic valve as a result of the valve's biomimetic design.
Drs. Amar Krishnaswamy, Nicolas Van Mieghem, and Bernard Prendergast review the latest DurAVR® THV MRI flow & LV mass data compared to a healthy control group, exploring the impact of valve design on laminar flow, disease regression, and patient outcomes.
At TCT 2024, Dr. Amar Krishnaswamy presented the latest MRI data analyses which compared flow dynamics and left ventricular function between DurAVR® THV recipients and a matched healthy control group. Here were some of the key takeaways:
In this matched analysis, DurAVR® THV’s biomimetic design provides flow patterns similar to the healthy valve, as measured by flow displacement (FD) and flow reversal ratios (FRR).
LV mass decreased in patients treated with DurAVR® THV compared to baseline, suggesting an improvement in LV unloading.
In this matched analysis, DurAVR® THV restored left ventricle (LV) end-diastolic volume, LV end-systolic volume, and LV mass to similar to healthy controls.
Watch leading experts in the field of TAVR discuss the biomimetic design of the DurAVR® THV and its impact on hemodynamics and blood flow dynamics, presented by Drs. Christopher Meduri, Susheel Kodali, João Cavalcante, Michael Reardon, Nicolas Van Mieghem, Azeem Latib, Anita Asgar and Vinayak Bapat.
Key takeaways included:
We are excited to share the promising results from a valve-in-valve (ViV) study led by Dr. Anita Asgar and recently presented at New York Valves. The data demonstrated restoration of hemodynamic performance in five complex cases in which patients underwent a DurAVR® Transcatheter Heart Valve implantation after their surgical replacement valves failed.
Dr. Asgar emphasized, “This data set of valve-in-valve patients highlights the impact of the DurAVR® valve biomimetic design by restoring these patients’ hemodynamics to the performance of their initial surgical valve and is very encouraging for the wave of valve-in-valve patients that are coming in the future.”
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